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1

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

Ines Batinic-Haberle, Ivan Spasojevic, Hubert M. Tse, Artak Tovmasyan, Zrinka Rajic, Daret K. St. Clair, Zeljko Vujaskovic, Mark W. Dewhirst, Jon D. Piganelli

Journal:

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

2

Erratum to: Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

Ines Batinic-Haberle, Ivan Spasojevic, Hubert M. Tse, Artak Tovmasyan, Zrinka Rajic, Daret K. St. Clair, Zeljko Vujaskovic, Mark W. Dewhirst, Jon D. Piganelli

Journal:

Year:

2012

Language:

english

File:

PDF, 209 KB

english, 2012

3

Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS)

Elizabeth J. Hager, Jon D. Piganelli, Hubert M. Tse, K. Michael Gibson

Journal:

Journal of Inherited Metabolic Disease

Year:

2012

Language:

english

File:

PDF, 365 KB

english, 2012

4

Autoreactive T-cell responses: new technology in pursuit of an old nemesis

Jon D Piganelli, Clayton E Mathews

Journal:

Pediatric Diabetes

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

5

Preeclampsia Activates Circulating Immune Cells with Engagement of the NF-κB Pathway

Patrizia Luppi, Hubert Tse, Kristine Y. Lain, Nina Markovic, Jon D. Piganelli, Julie A. DeLoia

Journal:

American Journal of Reproductive Immunology

Year:

2006

Language:

english

File:

PDF, 258 KB

english, 2006

6

Chromogranin A is an autoantigen in type 1 diabetes

Stadinski, Brian D, Delong, Thomas, Reisdorph, Nichole, Reisdorph, Richard, Powell, Roger L, Armstrong, Michael, Piganelli, Jon D, Barbour, Gene, Bradley, Brenda, Crawford, Frances

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 697 KB

english, 2010

7

Analysis of Leukocytes Recruited to the Pancreas by Diabetogenic T Cell Clones

Jeffrey D. Peterson, Rance Berg, Jon D. Piganelli, Michelle Poulin, Kathryn Haskins

Journal:

Cellular Immunology

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

8

Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation–reduction reactions in innate immunity

Hubert M Tse, Martha J Milton, Jon D Piganelli

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

9

Redox modulation inhibits CD8 T cell effector function

Martha M. Sklavos, Hubert M. Tse, Jon D. Piganelli

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 735 KB

english, 2008

10

Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat

Huaxin Sheng, Wei Yang, Shiro Fukuda, Hubert M. Tse, Wulf Paschen, Kwame Johnson, Ines Batinic-Haberle, James D. Crapo, Robert D. Pearlstein, Jon Piganelli, David S. Warner

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 438 KB

english, 2009

11

Enteric coated microspheres as an oral method for antigen delivery to salmonids

Jon D. Piganelli, Jia Allen Zhang, John M. Christensen, Stephen L. Kaattari

Journal:

Fish & Shellfish Immunology

Year:

1994

File:

PDF, 402 KB

1994

12

Cytotoxic T Lymphocyte Antigen 4 (CD152) Regulates Self-Reactive T cells in BALB/c but not in the Autoimmune NOD Mouse

Jon D Piganelli, Michelle Poulin, Tracy Martin, James P Allison, Kathryn Haskins

Journal:

Journal of Autoimmunity

Year:

2000

Language:

english

File:

PDF, 191 KB

english, 2000

13

Extracellular Superoxide Dismutase in Macrophages Augments Bacterial Killing by Promoting Phagocytosis

Michelle L. Manni, Lauren P. Tomai, Callie A. Norris, L. Michael Thomas, Eric E. Kelley, Russell D. Salter, James D. Crapo, Ling-Yi L. Chang, Simon C. Watkins, Jon D. Piganelli, Tim D. Oury

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.22 MB

english, 2011

14

Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-κB activation in vascular smooth muscle cells

Vincenza Cifarelli, Patrizia Luppi, Hubert M. Tse, Jing He, Jon Piganelli, Massimo Trucco

Journal:

Atherosclerosis

Year:

2008

Language:

english

File:

PDF, 2.23 MB

english, 2008

15

Effects of Metalloporphyrins on Reducing Inflammation and Autoimmunity

Delmastro-Greenwood, Meghan M., Tse, Hubert M., Piganelli, Jon D.

Journal:

Antioxidants & Redox Signaling

Year:

2014

Language:

english

File:

PDF, 472 KB

english, 2014

16

Activated Macrophages Create Lineage-Specific Microenvironments for Pancreatic Acinar- and β-Cell Regeneration in Mice

Criscimanna, Angela, Coudriet, Gina M., Gittes, George K., Piganelli, Jon D., Esni, Farzad

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 7.70 MB

english, 2014

17

Mn Porphyrin Regulation of Aerobic Glycolysis: Implications on the Activation of Diabetogenic Immune Cells

Delmastro-Greenwood, Meghan M., Votyakova, Tatyana, Goetzman, Eric, Marre, Meghan L., Previte, Dana M., Tovmasyan, Artak, Batinic-Haberle, Ines, Trucco, Massimo M., Piganelli, Jon D.

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 604 KB

english, 2013

18

PS13 - 69. Innate and adaptive immune activation of human BDCA1+ myeloid dendritic cells upon encountering enterovirus-infected β-cells

Schulte, Barbara M., Kers-Rebel, Esther D., Galama, Jochem M.D., Bottino, Rita, Piganelli, Jon D., van Kuppeveld, Frank J. M., Adema, Gosse J.

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2011

Language:

english

File:

PDF, 206 KB

english, 2011

19

PS2 - 10. Enterovirus-Infected Human Pancreatic Islets Produce Pro-inflammatory Cytokines and Chemokines and Activate Primary Human Myeloid Dendritic Cells

Schulte, Barbara M., Kers-Rebel, Esther D., Lanke, Kjerstin H.W., Engelse, Marten A., de Koning, Eelco J.P., Bottino, Rita, Piganelli, Jon D., van Kuppeveld, Frank J. M., Adema, Gosse J.

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

20

Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes

Delmastro, Meghan M., Piganelli, Jon D.

Journal:

Clinical & Developmental Immunology

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

21

Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice

Calabuig-Navarro, Virtu, Yamauchi, Jun, Lee, Sojin, Zhang, Ting, Liu, Yun-Zi, Sadlek, Kelsey, Coudriet, Gina M., Piganelli, Jon D., Jiang, Chun-Lei, Miller, Rita, Lowe, Mark, Harashima, Hideyoshi, Don

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 3.70 MB

english, 2015

22

T Cell Epitopes and Post-Translationally Modified Epitopes in Type 1 Diabetes

McGinty, John W., Marré, Meghan L., Bajzik, Veronique, Piganelli, Jon D., James, Eddie A.

Journal:

Current Diabetes Reports

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

23

Loss of NOX-derived superoxide exacerbates diabetogenic CD4 T cell effector responses in Type 1 Diabetes

Padgett, Lindsey E., Anderson, Brian, Liu, Chao, Ganini, Douglas, Mason, Ronald P., Piganelli, Jon D., Mathews, Clayton E., Tse, Hubert M.

Journal:

Year:

2015

Language:

english

File:

PDF, 4.50 MB

english, 2015

24

Endoscopic biopsy of islet transplants in the gastric submucosal space provides evidence of islet graft rejection in diabetic pigs

Tanaka, Takayuki, Fujita, Minoru, Bottino, Rita, Piganelli, Jon D., McGrath, Kevin, Li, Jiang, Lee, Whayoung, Iwase, Hayato, Wijkstrom, Martin, Bertera, Suzanne, Long, Cassandra, Landsittel, Douglas,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

25

Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes

Marré, Meghan L., Profozich, Jennifer L., Coneybeer, Jorge T., Geng, Xuehui, Bertera, Suzanne, Ford, Michael J., Trucco, Massimo, Piganelli, Jon D.

Journal:

Journal of Autoimmunity

Year:

2016

Language:

english

File:

PDF, 2.12 MB

english, 2016

26

A novel redox-active metalloporphyrin reduces reactive oxygen species and inflammatory markers but does not improve marginal mass engraftment in a murine donation after circulatory death islet transplantation model

Bruni, Antonio, Pepper, Andrew R., Gala-Lopez, Boris, Pawlick, Rena, Abualhassan, Nasser, Crapo, James D., Piganelli, Jon D., Shapiro, A. M. James

Journal:

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

27

Human-Scale Whole-Organ Bioengineering for Liver Transplantation: A Regenerative Medicine Approach

Yagi, Hiroshi, Fukumitsu, Ken, Fukuda, Kazumasa, Kitago, Minoru, Shinoda, Masahiro, Obara, Hideaki, Itano, Osamu, Kawachi, Shigeyuki, Tanabe, Minoru, Coudriet, Gina M., Piganelli, Jon D., Gilbert, Tho

Journal:

Cell Transplantation

Year:

2013

Language:

english

File:

PDF, 535 KB

english, 2013

28

Reactive Oxygen Species and their Implications on CD4+ T cells in Type 1 Diabetes

Previte, Dana M, Piganelli, Jon D.

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 691 KB

english, 2017

29

Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes

Xiao, Xiangwei, Guo, Ping, Shiota, Chiyo, Zhang, Ting, Coudriet, Gina M., Fischbach, Shane, Prasadan, Krishna, Fusco, Joseph, Ramachandran, Sabarinathan, Witkowski, Piotr, Piganelli, Jon D., Gittes, G

Journal:

Year:

2018

Language:

english

File:

PDF, 5.01 MB

english, 2018

30

BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model

Bruni, Antonio, Pepper, Andrew R., Pawlick, Rena L., Gala-Lopez, Boris, Gamble, Anissa, Kin, Tatsuya, Malcolm, Andrew J., Jones, Carissa, Piganelli, Jon D., Crapo, James D., Shapiro, A.M. James

Journal:

American Journal of Transplantation

Year:

2018

Language:

english

File:

PDF, 799 KB

english, 2018

31

ATF4 Regulates CD4 + T Cell Immune Responses through Metabolic Reprogramming

Yang, Xi, Xia, Rui, Yue, Cuihua, Zhai, Wensi, Du, Wenwen, Yang, Qianting, Cao, Huiling, Chen, Xiaojuan, Obando, Danielle, Zhu, Yibei, Chen, Xinchun, Chen, Jane-Jane, Piganelli, Jon, Wipf, Peter, Jiang

Journal:

Year:

2018

Language:

english

File:

PDF, 3.32 MB

english, 2018

32

Lack of the Receptor for Advanced Glycation End-Products Attenuates E. coli Pneumonia in Mice

Ramsgaard, Lasse, Englert, Judson M., Manni, Michelle L., Milutinovic, Pavle S., Gefter, Julia, Tobolewski, Jacob, Crum, Lauren, Coudriet, Gina M., Piganelli, Jon, Zamora, Ruben, Vodovotz, Yoram, Engh

Journal:

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

33

Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation

Previte, Dana M., O’Connor, Erin C., Novak, Elizabeth A., Martins, Christina P., Mollen, Kevin P., Piganelli, Jon D., Tan, Ming

Journal:

Year:

2017

Language:

english

File:

PDF, 6.49 MB

english, 2017

34

Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes

Coudriet, Gina, Delmastro-Greenwood, Meghan, Previte, Dana, Marré, Meghan, O’Connor, Erin, Novak, Elizabeth, Vincent, Garret, Mollen, Kevin, Lee, Sojin, Dong, H., Piganelli, Jon

Journal:

Year:

2017

Language:

english

File:

PDF, 4.59 MB

english, 2017

35

β cell ER stress and the implications for immunogenicity in type 1 diabetes

Marré, Meghan L., James, Eddie A., Piganelli, Jon D.

Journal:

Frontiers in Cell and Developmental Biology

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

36

Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes

Marré, Meghan L., Piganelli, Jon D.

Journal:

Frontiers in Endocrinology

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

37

T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis

Ferguson, Ian D., Griffin, Patricia, Michel, Joshua J., Yano, Hiroshi, Gaffen, Sarah L., Mueller, Robert G., Dvergsten, Jeffrey A., Piganelli, Jon D., Rosenkranz, Margalit E., Kietz, Daniel A., Vallej

Journal:

Frontiers in Immunology

Year:

2018

File:

PDF, 6.46 MB

2018

38

Calcium/calmodulin–dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation

Cunningham, Kellie E., Novak, Elizabeth A., Vincent, Garret, Siow, Vei Shaun, Griffith, Brian D., Ranganathan, Sarangarajan, Rosengart, Matthew R., Piganelli, Jon D., Mollen, Kevin P.

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 4.24 MB

english, 2018

39

T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis

Ferguson, Ian D., Griffin, Patricia, Michel, Joshua J., Yano, Hiroshi, Gaffen, Sarah L., Mueller, Robert G., Dvergsten, Jeffrey A., Piganelli, Jon D., Rosenkranz, Margalit E., Kietz, Daniel A., Vallej

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 6.46 MB

english, 2018

40

Poly(ADP-Ribose) Polymerase 1-Sirtuin 1 Functional Interplay Regulates LPS-Mediated High Mobility Group Box 1 Secretion

Walko, Thomas D., Di Caro, Valentina, Piganelli, Jon, Billiar, Timothy R., Clark, Robert S. B., Aneja, Rajesh K.

Journal:

Molecular Medicine

Year:

2014

File:

PDF, 5.05 MB

2014

41

A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes

Coudriet, Gina M., Stoops, John, Orr, Anne V., Bhushan, Bharat, Koral, Kelly, Lee, Sojin, Previte, Dana M., Dong, H. Henry, Michalopoulos, George K., Mars, Wendy M., Piganelli, Jon D.

Journal:

The American Journal of Pathology

Year:

2019

Language:

english

File:

PDF, 8.60 MB

english, 2019

42

Dietary Cellulose Supplementation Modulates the Immune Response in a Murine Endotoxemia Model

Di Caro, Valentina, Cummings, Jessica L., Alcamo, Alicia M., Piganelli, Jon D., Clark, Robert S.B., Morowitz, Michael J., Aneja, Rajesh K.

Journal:

Year:

2019

File:

PDF, 1.17 MB

2019

43

TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model

Bassin, Ethan J., Buckley, Abigail R., Piganelli, Jon D., Little, Steven R., Choi, Je-Min

Journal:

Year:

2020

File:

PDF, 1.31 MB

2020

44

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] B28. OXIDATIVE STRESS, SIGNAL TRANSDUCTION AND MECHANISMS OF LUNG INJURY - Extracellular Superoxide Dismutase Modulates Bacterial Phagocytosis And Promotes Resolution Of Inflammation In Response To Bacterial Pneumonia

Manni, Michelle L., Tomai, Lauren P., Thomas, L. M., Norris, Callie A., Kelley, Eric E., Salter, Russell D., Freeman, Bruce A., Watkins, Simon C., Piganelli, Jon D., Oury, Tim D.

Year:

2010

File:

PDF, 17 KB

2010

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